Metropolis Healthcare’s study identifies 1,142 low-risk pregnancies with reflex testing

New Delhi: Metropolis Healthcare Limited has revealed insights from a three-year study involving more than 140,000 expectant mothers.

The study focused on enhancing the accuracy of prenatal screening through a combination of Pregascreen Reflex Testing and Non-invasive Prenatal Testing (NIPT) or Karyotyping. 

The study revealed initially, out of 140,528 pregnancies, traditional early trimester screenings identified 5,879 as high-risk cases. However, the integration of NIPT with Pregascreen reflex testing enhanced accuracy in identifying genuine high-risk cases.

During the first trimester, dual marker testing identified 2,416 cases as high-risk. Yet, upon NIPT reflex testing, only 64 of these remained classified as high-risk, accurately reclassifying 1,142 cases as low-risk. Similarly, in the second trimester, among 3,463 cases flagged by the Quadruple marker, NIPT accurately reassigned 455 cases as low risk, with only 20 still considered high risk.

Surendran Chemmenkotil, Chief Executive Officer of Metropolis Healthcare Limited, stated, “Our pioneering Reflex Testing developed several years ago, delivers comprehensive and conclusive diagnoses, saving time and reducing the additional cost burden for patients. We are dedicated to advancing maternal health testing through innovative diagnostic tools and advanced screening technologies. Our vision is to establish Metropolis as a center of excellence in Women and Child healthcare, empowering patients and healthcare providers with essential knowledge for informed decisions and fostering awareness through extensive research studies.”

Dr Kirti Chadha, Chief Scientific and Innovation Officer at Metropolis Healthcare Limited highlighted, “The Pregascreen Reflex Test is a cost-effective scientific methodology that significantly outperforms traditional screening methods. It’s not only non-invasive and quick but also minimizes the risk of miscarriage. It allows for the early detection of chromosomal abnormalities, which can significantly alleviate potential psychological trauma for expectant parents. And proves to be highly accurate in detecting fetal chromosomal abnormalities early in pregnancy. This substantially reduces the emotional and psychological strain on expectant mothers and their families.”